TORC1 Rabbit pAb
Cat#:DPA01750应用:WB,ICC/IF,FC
Product Name: | TORC1 Rabbit pAb |
Cat No.: | DPA04453 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human TORC1 |
Calculated Molecular Weight: | 67 kDa |
Observed Molecular Weight: | 78 kDa |
GenBank Accession Number: | Q6UUV9 |
Gene ID (NCBI): | 23373 |
Synonyms: | MECT1; TORC1; TORC-1; WAMTP1 |
Background: | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. |
Category: | Primary Ab |