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TORC1 Rabbit pAb

Cat No.: DPA04453
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Product Name: TORC1 Rabbit pAb
Cat No.: DPA04453
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human TORC1
Calculated Molecular Weight: 67 kDa
Observed Molecular Weight: 78 kDa
GenBank Accession Number: Q6UUV9
Gene ID (NCBI): 23373
Synonyms: MECT1; TORC1; TORC-1; WAMTP1
Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.
Category: Primary Ab
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