蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书MSH3 Rabbit pAb
Cat#:DPA04457应用：IHC,ICC/IF
| Product Name: | MSH3 Rabbit pAb |
| Cat No.: | DPA04457 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | IHC,ICC/IF |
| Recommended Dilution: | IHC: 1:50-1:200 ICC/IF: 1:50-1:200 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MSH3 |
| Calculated Molecular Weight: | 127 kDa |
| GenBank Accession Number: | P20585 |
| Gene ID (NCBI): | 4437 |
| Synonyms: | DUP; FAP4; MRP1 |
| Background: | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011] |
| Category: | Primary Ab |
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