蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PHOX2B Rabbit pAb
Cat#:DPA04514应用：WB,IHC,ICC/IF
| Product Name: | PHOX2B Rabbit pAb |
| Cat No.: | DPA04514 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human PHOX2B |
| Calculated Molecular Weight: | 32 kDa |
| Observed Molecular Weight: | 32 kDa |
| GenBank Accession Number: | Q99453 |
| Gene ID (NCBI): | 8929 |
| Synonyms: | PMX2B; NBLST2; NBPhox |
| Background: | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016] |
| Category: | Primary Ab |
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