TRPM8 Rabbit pAb
Cat#:DPA04545应用:WB,ICC/IF
Product Name: | TRPM8 Rabbit pAb |
Cat No.: | DPA04545 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse |
Tested Applications: | WB,ICC/IF |
Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:50-1:200 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human TRPM8 |
Calculated Molecular Weight: | 128 kDa |
Observed Molecular Weight: | 128 kDa |
GenBank Accession Number: | Q7Z2W7 |
Gene ID (NCBI): | 79054 |
Synonyms: | TRPP8; LTRPC6; trp-p8; LTrpC-6 |
Background: | Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. |
Category: | Primary Ab |