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分子生物学
规格：
查看说明书RNF20 Rabbit pAb
Cat#:DPA04583应用：WB,ICC/IF,FC,IP
| Product Name: | RNF20 Rabbit pAb |
| Cat No.: | DPA04583 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20-1:50 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human RNF20 |
| Calculated Molecular Weight: | 114 kDa |
| Observed Molecular Weight: | 120 kDa |
| GenBank Accession Number: | Q5VTR2 |
| Gene ID (NCBI): | 56254 |
| Synonyms: | BRE1; BRE1A; hBRE1 |
| Background: | The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012] |
| Category: | Primary Ab |
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