FGR Rabbit pAb
Cat#:DPA04600应用:WB,ICC/IF
| Product Name: | FGR Rabbit pAb |
| Cat No.: | DPA04600 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human FGR |
| Calculated Molecular Weight: | 60 kDa |
| Observed Molecular Weight: | 60 kDa |
| GenBank Accession Number: | P09769 |
| Gene ID (NCBI): | 2268 |
| Synonyms: | SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr |
| Background: | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |