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FGR Rabbit pAb

Cat No.: DPA04600
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Product Name: FGR Rabbit pAb
Cat No.: DPA04600
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF
Recommended Dilution: WB: 1:1000-1:5000
ICC/IF: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human FGR
Calculated Molecular Weight: 60 kDa
Observed Molecular Weight: 60 kDa
GenBank Accession Number: P09769
Gene ID (NCBI): 2268
Synonyms: SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr
Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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