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Plastin L Rabbit pAb

Cat No.: DPA04668
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Product Name: Plastin L Rabbit pAb
Cat No.: DPA04668
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Plastin L
Calculated Molecular Weight: 70 kDa
Observed Molecular Weight: 70 kDa
GenBank Accession Number: P13796
Gene ID (NCBI): 3936
Synonyms: LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN
Background: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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