蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书ABCD1 Rabbit pAb
Cat#:DPA04693应用：WB,ICC/IF,FC
| Product Name: | ABCD1 Rabbit pAb |
| Cat No.: | DPA04693 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,FC |
| Recommended Dilution: | WB: 1:2000 ICC/IF: 1:20 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human ABCD1 |
| Calculated Molecular Weight: | 83 kDa |
| Observed Molecular Weight: | 83 kDa |
| GenBank Accession Number: | P33897 |
| Gene ID (NCBI): | 215 |
| Synonyms: | ALD; AMN; ALDP; ABC42 |
| Background: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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