Zonula occludens protein 3 Rabbit pAb
Cat#:DPA02760应用:WB
Product Name: | Zonula occludens protein 3 Recombinant Rabbit mAb |
Cat No.: | RMA01978 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Zonula occludens protein 3 |
Calculated Molecular Weight: | 101 kDa |
Observed Molecular Weight: | 140 kDa |
GenBank Accession Number: | O95049 |
Gene ID (NCBI): | 27134 |
Synonyms: | ZO3; ZO-3 |
Background: | The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012] |
Category: | Primary Ab |