蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Zonula occludens protein 3 Rabbit pAb
Cat#:DPA02760应用：WB
| Product Name: | Zonula occludens protein 3 Rabbit pAb |
| Cat No.: | DPA02760 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:2000-1:10000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Zonula occludens protein 3 |
| Calculated Molecular Weight: | 101 kDa |
| Observed Molecular Weight: | 140 kDa |
| GenBank Accession Number: | O95049 |
| Gene ID (NCBI): | 27134 |
| Synonyms: | ZO3; ZO-3 |
| Background: | The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012] |
| Category: | Primary Ab |
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