Cat No.: RMA01998

规格：

Western blot analysis of Anti-PCGF6 antibody(RMA01998) Gel: 15%SDS-PAGE Lysate: 20 μg Primary antibody: RMA01998(PCGF6 antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name:	PCGF6 Recombinant Rabbit mAb
Cat No.:	RMA01998
Clonality:	Monoclonal
Species Reactivity:	Mouse, Rat
Tested Applications:	WB,ICC/IF,IP
Recommended Dilution:	WB,ICC/IF,IP
Size:	30ul 50ul 100uL
Format:	Liquid
Source:	Rabbit
Purification Method:	Affinity Purification
Isotype:	IgG
Conjugate:	Un-conjugated
Storage:	Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen:	Recombinant protein of mouse PCGF6
Calculated Molecular Weight:	40 kDa
Observed Molecular Weight:	40 kDa
GenBank Accession Number:	Q99NA9
Gene ID (NCBI):	71041
Synonyms:	MBLR; Rnf134; AI604840; 4933407A11Rik
Background:	Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.
Category:	Primary Ab

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