蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PCGF6 Rabbit pAb
Cat#:DPA02721应用：WB,ICC/IF,IP
| Product Name: | PCGF6 Rabbit pAb |
| Cat No.: | DPA02721 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse, Rat |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse PCGF6 |
| Calculated Molecular Weight: | 40 kDa |
| Observed Molecular Weight: | 40 kDa |
| GenBank Accession Number: | Q99NA9 |
| Gene ID (NCBI): | 71041 |
| Synonyms: | MBLR; Rnf134; AI604840; 4933407A11Rik |
| Background: | Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. |
| Category: | Primary Ab |
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