Integrin alpha 4/CD49D Rabbit pAb
Cat#:DPA02066应用:WB
| Product Name: | Phospho-Integrin alpha 4 (Ser1027) Rabbit pAb |
| Cat No.: | DPA05635 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser1027 of human Integrin alpha 4 |
| Calculated Molecular Weight: | 115 kDa |
| Observed Molecular Weight: | 150,70 kDa |
| GenBank Accession Number: | P13612 |
| Gene ID (NCBI): | 3676 |
| Synonyms: | IA4; CD49D |
| Background: | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Category: | Primary Ab |