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Integrin alpha 4/CD49D Rabbit pAb

Cat No.: DPA02066
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Product Name: Integrin alpha 4/CD49D Rabbit pAb
Cat No.: DPA02066
Clonality: Polyclonal
Species Reactivity: Human, Mouse
Tested Applications: WB
Recommended Dilution: WB: 1:1000
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Integrin alpha 4/CD49D
Calculated Molecular Weight: 115 kDa
Observed Molecular Weight: 150,70 kDa
GenBank Accession Number: P13612
Gene ID (NCBI): 3676
Synonyms: IA4; CD49D
Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Category: Primary Ab
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